New preprint!
Thrilled to share our latest preprint reporting the pro-regenerative effects of senolytic CAR T cells in the aged gut. Important implications for the use of CAR T cells in regenerative medicine!
Our laboratory studies aging with the goal to improve healthspan and find effective treatments for age-related diseases. To do this, we focus on understanding the biology of senescent cells, dysfunctional cells that accumulate in organisms over time and drive aging diseases.
We pioneer the development of CAR T cells able to eliminate these senescent cells. In our studies we harness senolytic cell therapy to both understand the biology of senescent cells and to develop new therapeutic strategies.
